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A caspase-6-cleaved fragment of Glial Fibrillary Acidic Protein as a potential serological biomarker of CNS injury after cardiac arrest

Blood levels of Glial Fibrillary Acidic protein (GFAP) reflect processes associated with different types of CNS injury. Evidence suggests that GFAP is cleaved by caspases during CNS injury, hence positioning GFAP fragments as potential biomarkers of injury-associated processes. We set out to develop...

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Detalles Bibliográficos
Autores principales: Jonesco, Ditte S., Hassager, Christian, Frydland, Martin, Kjærgaard, Jesper, Karsdal, Morten, Henriksen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834260/
https://www.ncbi.nlm.nih.gov/pubmed/31693684
http://dx.doi.org/10.1371/journal.pone.0224633