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Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance

Evolved resistance to one antibiotic may be associated with "collateral" sensitivity to other drugs. Here, we provide an extensive quantitative characterization of collateral effects in Enterococcus faecalis, a gram-positive opportunistic pathogen. By combining parallel experimental evolut...

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Detalles Bibliográficos
Autores principales: Maltas, Jeff, Wood, Kevin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834293/
https://www.ncbi.nlm.nih.gov/pubmed/31652256
http://dx.doi.org/10.1371/journal.pbio.3000515