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Cytoprotective Preconditioning of Osteoblast-Like Cells with N-Acetyl-L-Cysteine for Bone Regeneration in Cell Therapy

Oxidative stress hinders tissue regeneration in cell therapy by inducing apoptosis and dysfunction in transplanted cells. N-acetyl-L-cysteine (NAC) reinforces cellular antioxidant capabilities by increasing a major cellular endogenous antioxidant molecule, glutathione, and promotes osteogenic differ...

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Detalles Bibliográficos
Autores principales: Yamada, Masahiro, Watanabe, Jun, Ueno, Takeshi, Ogawa, Takahiro, Egusa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834301/
https://www.ncbi.nlm.nih.gov/pubmed/31635184
http://dx.doi.org/10.3390/ijms20205199