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The GATOR complex regulates an essential response to meiotic double-stranded breaks in Drosophila

The TORC1 regulator GATOR1/SEACIT controls meiotic entry and early meiotic events in yeast. However, how metabolic pathways influence meiotic progression in metazoans remains poorly understood. Here we examine the role of the TORC1 regulators GATOR1 and GATOR2 in the response to meiotic double-stran...

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Detalles Bibliográficos
Autores principales: Wei, Youheng, Bettedi, Lucia, Ting, Chun-Yuan, Kim, Kuikwon, Zhang, Yingbiao, Cai, Jiadong, Lilly, Mary A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834368/
https://www.ncbi.nlm.nih.gov/pubmed/31650955
http://dx.doi.org/10.7554/eLife.42149