Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies

Enhancing the therapeutic efficacy of drugs for inflammatory diseases is of high demand. One possible approach is targeting drugs to the extracellular matrix of the inflamed area. Here, we target collagens in the matrix, which are inaccessible in most tissues yet are exposed to the bloodstream in th...

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Detalles Bibliográficos
Autores principales: Katsumata, Kiyomitsu, Ishihara, Jun, Mansurov, Aslan, Ishihara, Ako, Raczy, Michal M., Yuba, Eiji, Hubbell, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834392/
https://www.ncbi.nlm.nih.gov/pubmed/31723606
http://dx.doi.org/10.1126/sciadv.aay1971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834392/
https://www.ncbi.nlm.nih.gov/pubmed/31723606
http://dx.doi.org/10.1126/sciadv.aay1971

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