Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression

Diabetic nephropathy (DN) is one of the leading causes of end-stage renal diseases worldwide. This study is designed to investigate the underlying function and mechanism of a novel lncRNA GAS5 in the progression of DN. We found that lncRNA GAS5 expression level was decreased in type 2 diabetes (T2D)...

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Detalles Bibliográficos
Autores principales: Ge, Xiaoxu, Xu, Bojin, Xu, Wenwei, Xia, Lili, Xu, Zhongqin, Shen, Lisha, Peng, Wenfang, Huang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398/
https://www.ncbi.nlm.nih.gov/pubmed/31631065
http://dx.doi.org/10.18632/aging.102249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398/
https://www.ncbi.nlm.nih.gov/pubmed/31631065
http://dx.doi.org/10.18632/aging.102249

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