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Overexpression of steroid sulfotransferase genes is associated with worsened prognosis and with immune exclusion in clear cell-renal cell carcinoma

Aim: Steroid sulfotransferase (SULT) plays physiological roles but its role in clear cell-renal cell carcinoma (ccRCC) remains unclear. We therefore investigated genetic alteration of steroid SULT genes in ccRCC. Results: Overexpression of any of SULT genes occurred in ~8% of ccRCC patients. Overexp...

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Detalles Bibliográficos
Autores principales: Li, Yuqing, Ding, Qiang, Xiong, Zuquan, Wen, Hui, Feng, Chenchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834411/
https://www.ncbi.nlm.nih.gov/pubmed/31655797
http://dx.doi.org/10.18632/aging.102392