Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity

Background: Mitochondrial dysfunction and oxidative stress are closely associated with the pathogenesis of Parkinson’s disease. Peroxisome proliferator-activated receptor γ coactivator 1 alpha (PGC-1α) is thought to play multiple roles in the regulation of mitochondrial biogenesis and cellular energ...

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Detalles Bibliográficos
Autores principales: Wang, Yingqing, Chen, Chun, Huang, Wanling, Huang, Maoxin, Wang, Juhua, Chen, Xiaochun, Ye, Qinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834419/
https://www.ncbi.nlm.nih.gov/pubmed/31634150
http://dx.doi.org/10.18632/aging.102357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834419/
https://www.ncbi.nlm.nih.gov/pubmed/31634150
http://dx.doi.org/10.18632/aging.102357

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