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Sirtuin 3 attenuates neuroinflammation-induced apoptosis in BV-2 microglia

In this study, we explored the upstream regulatory mechanisms underlying inflammation-induced mitochondrial dysfunction in microglial BV-2 cells. Our results demonstrate that Sirtuin 3 (Sirt3) expression was downregulated in response to LPS-induced neuroinflammation. In addition, overexpression of S...

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Detalles Bibliográficos
Autores principales: Zhou, Dingzhou, Jiang, Yugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834423/
https://www.ncbi.nlm.nih.gov/pubmed/31631063
http://dx.doi.org/10.18632/aging.102375