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Sirtuin 3 attenuates neuroinflammation-induced apoptosis in BV-2 microglia
In this study, we explored the upstream regulatory mechanisms underlying inflammation-induced mitochondrial dysfunction in microglial BV-2 cells. Our results demonstrate that Sirtuin 3 (Sirt3) expression was downregulated in response to LPS-induced neuroinflammation. In addition, overexpression of S...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834423/ https://www.ncbi.nlm.nih.gov/pubmed/31631063 http://dx.doi.org/10.18632/aging.102375 |