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Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity

Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria. In fish, they have received little attention to their existence, classifica...

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Detalles Bibliográficos
Autores principales: Chaves-Pozo, Elena, Valero, Yulema, Lozano, Maria Teresa, Rodríguez-Cerezo, Pablo, Miao, Liang, Campo, Vittorio, Esteban, Maria Angeles, Cuesta, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834543/
https://www.ncbi.nlm.nih.gov/pubmed/31736981
http://dx.doi.org/10.3389/fimmu.2019.02579