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Boosting Recombinant Inclusion Body Production—From Classical Fed-Batch Approach to Continuous Cultivation

State of the art microbial recombinant protein production is regularly performed in fed-batch based cultivations. However, these cultivations suffer from highly time-dependent changes in productivity and product quality, leading to high variations in the downstream process. Continuous biomanufacturi...

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Detalles Bibliográficos
Autores principales: Kopp, Julian, Kolkmann, Anna-Maria, Veleenturf, Patrick Gwen, Spadiut, Oliver, Herwig, Christoph, Slouka, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834550/
https://www.ncbi.nlm.nih.gov/pubmed/31737617
http://dx.doi.org/10.3389/fbioe.2019.00297