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Boosting Recombinant Inclusion Body Production—From Classical Fed-Batch Approach to Continuous Cultivation
State of the art microbial recombinant protein production is regularly performed in fed-batch based cultivations. However, these cultivations suffer from highly time-dependent changes in productivity and product quality, leading to high variations in the downstream process. Continuous biomanufacturi...
Autores principales: | Kopp, Julian, Kolkmann, Anna-Maria, Veleenturf, Patrick Gwen, Spadiut, Oliver, Herwig, Christoph, Slouka, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834550/ https://www.ncbi.nlm.nih.gov/pubmed/31737617 http://dx.doi.org/10.3389/fbioe.2019.00297 |
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