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EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming

The molecular mechanisms driving metastatic progression in triple-negative breast cancer (TNBC) patients are poorly understood. In this study, we demonstrate that epidermal growth factor-like 9 (EGFL9) is significantly upregulated in basal-like breast cancer cells and associated with metastatic prog...

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Detalles Bibliográficos
Autores principales: Meng, Fanyan, Wu, Ling, Dong, Lun, Mitchell, Allison V., James Block, C., Liu, Jenney, Zhang, Haijun, Lu, Qing, Song, Won-min, Zhang, Bin, Chen, Wei, Hu, Jiani, Wang, Jian, Yang, Qifeng, Hüttemann, Maik, Wu, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834558/
https://www.ncbi.nlm.nih.gov/pubmed/31695034
http://dx.doi.org/10.1038/s41467-019-13034-3