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Hif1a and Hif2a can be safely inactivated in cone photoreceptors

Impaired tissue oxygenation results in hypoxia and leads to the activation of hypoxia-inducible transcription factors (HIF). A chronic, HIF-triggered molecular response to hypoxia may be an important factor in the etiology of age-related macular degeneration (AMD) and is likely activated before any...

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Detalles Bibliográficos
Autores principales: Samardzija, Marijana, Barben, Maya, Todorova, Vyara, Klee, Katrin, Storti, Federica, Grimm, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834587/
https://www.ncbi.nlm.nih.gov/pubmed/31695081
http://dx.doi.org/10.1038/s41598-019-52508-8