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Hif1a and Hif2a can be safely inactivated in cone photoreceptors
Impaired tissue oxygenation results in hypoxia and leads to the activation of hypoxia-inducible transcription factors (HIF). A chronic, HIF-triggered molecular response to hypoxia may be an important factor in the etiology of age-related macular degeneration (AMD) and is likely activated before any...
Autores principales: | Samardzija, Marijana, Barben, Maya, Todorova, Vyara, Klee, Katrin, Storti, Federica, Grimm, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834587/ https://www.ncbi.nlm.nih.gov/pubmed/31695081 http://dx.doi.org/10.1038/s41598-019-52508-8 |
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