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Chemical activation of divergent protein tyrosine phosphatase domains with cyanine-based biarsenicals
Strategies for the direct chemical activation of specific signaling proteins could provide powerful tools for interrogating cellular signal transduction. However, targeted protein activation is chemically challenging, and few broadly applicable activation strategies for signaling enzymes have been d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834593/ https://www.ncbi.nlm.nih.gov/pubmed/31695052 http://dx.doi.org/10.1038/s41598-019-52002-1 |