Structure and regulation of ZCCHC4 in m(6)A-methylation of 28S rRNA

N(6)-methyladenosine (m(6)A) modification provides an important epitranscriptomic mechanism that critically regulates RNA metabolism and function. However, how m(6)A writers attain substrate specificities remains unclear. We report the 3.1 Å-resolution crystal structure of human CCHC zinc finger-con...

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Detalles Bibliográficos
Autores principales: Ren, Wendan, Lu, Jiuwei, Huang, Mengjiang, Gao, Linfeng, Li, Dongxu, Wang, Gang Greg, Song, Jikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834594/
https://www.ncbi.nlm.nih.gov/pubmed/31695039
http://dx.doi.org/10.1038/s41467-019-12923-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834594/
https://www.ncbi.nlm.nih.gov/pubmed/31695039
http://dx.doi.org/10.1038/s41467-019-12923-x

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