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Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells

The trabecular meshwork (TM) is a specialized ocular tissue, which is responsible, together with the Schlemm’s canal (SC), for maintaining appropriate levels of intraocular pressure. Dysfunction of these tissues leads to ocular hypertension and increases the risk for developing glaucoma. Previous wo...

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Detalles Bibliográficos
Autores principales: Nettesheim, April, Shim, Myoung Sup, Hirt, Josh, Liton, Paloma B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834604/
https://www.ncbi.nlm.nih.gov/pubmed/31695131
http://dx.doi.org/10.1038/s41598-019-52627-2