Extensive Expression Analysis of Htt Transcripts in Brain Regions from the zQ175 HD Mouse Model Using a QuantiGene Multiplex Assay

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by a CAG repeat expansion within exon 1 of the huntingtin (HTT) gene. HTT mRNA contains 67 exons and does not always splice between exon 1 and exon 2 leading to the production of a small polyadenylated HTTexon1 transcript, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Papadopoulou, Aikaterini S., Gomez-Paredes, Casandra, Mason, Michael A., Taxy, Bridget A., Howland, David, Bates, Gillian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834638/
https://www.ncbi.nlm.nih.gov/pubmed/31695145
http://dx.doi.org/10.1038/s41598-019-52411-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834638/
https://www.ncbi.nlm.nih.gov/pubmed/31695145
http://dx.doi.org/10.1038/s41598-019-52411-2

Ejemplares similares