A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence

The senescence response to oncogenes is believed to be a barrier to oncogenic transformation in premalignant lesions, and describing the mechanisms by which tumor cells evade this response is important for early diagnosis and treatment. The male germ cell-associated protein SSX2 is ectopically expre...

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Detalles Bibliográficos
Autores principales: Brückmann, Nadine H., Bennedsen, Sofie N., Duijf, Pascal H. G., Terp, Mikkel G., Thomassen, Mads, Larsen, Martin, Pedersen, Christina B., Kruse, Torben, Alcaraz, Nicolas, Ditzel, Henrik J., Gjerstorff, Morten F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834653/
https://www.ncbi.nlm.nih.gov/pubmed/31695025
http://dx.doi.org/10.1038/s41419-019-2068-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834653/
https://www.ncbi.nlm.nih.gov/pubmed/31695025
http://dx.doi.org/10.1038/s41419-019-2068-1

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