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MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer

Colorectal cancer (CRC) is one of the most common malignant tumors worldwide and understanding its underlying molecular mechanisms is crucial for the development of therapeutic strategies. The mitogen-activated protein kinase-kinase 3 (MKK3) is a specific activator of p38 MAP kinases (p38 MAPKs), wh...

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Detalles Bibliográficos
Autores principales: Stramucci, Lorenzo, Pranteda, Angelina, Stravato, Arianna, Amoreo, Carla Azzurra, Pennetti, Annarita, Diodoro, Maria Grazia, Bartolazzi, Armando, Milella, Michele, Bossi, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834673/
https://www.ncbi.nlm.nih.gov/pubmed/31695024
http://dx.doi.org/10.1038/s41419-019-2083-2