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Differential effects of D-cycloserine and amantadine on motor behavior and D(2/3) receptor binding in the nigrostriatal and mesolimbic system of the adult rat

D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects of DCS and AMA on dopamine D(2/3)R binding in the brain of adult rats in relation to motor behavior. D(2/3)R binding was determined with small...

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Detalles Bibliográficos
Autores principales: Nikolaus, Susanne, Wittsack, Hans-Jörg, Wickrath, Frithjof, Müller-Lutz, Anja, Hautzel, Hubertus, Beu, Markus, Antke, Christina, Mamlins, Eduards, De Souza Silva, Maria Angelica, Huston, Joseph P., Antoch, Gerald, Müller, Hans-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834679/
https://www.ncbi.nlm.nih.gov/pubmed/31695055
http://dx.doi.org/10.1038/s41598-019-52185-7