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Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction

Type 1 Diabetes (T1D) is an autoimmune disease that is associated with effector T cell (Teff) destruction of insulin-producing pancreatic beta-islet cells. Among the therapies being evaluated for T1D is the restoration of regulatory T cell (Treg) activity, specifically directed toward down-modulatio...

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Detalles Bibliográficos
Autores principales: De Groot, Anne S., Skowron, Gail, White, James Robert, Boyle, Christine, Richard, Guilhem, Serreze, David, Martin, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834854/
https://www.ncbi.nlm.nih.gov/pubmed/31695065
http://dx.doi.org/10.1038/s41598-019-52331-1