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Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction
Type 1 Diabetes (T1D) is an autoimmune disease that is associated with effector T cell (Teff) destruction of insulin-producing pancreatic beta-islet cells. Among the therapies being evaluated for T1D is the restoration of regulatory T cell (Treg) activity, specifically directed toward down-modulatio...
Autores principales: | De Groot, Anne S., Skowron, Gail, White, James Robert, Boyle, Christine, Richard, Guilhem, Serreze, David, Martin, William D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834854/ https://www.ncbi.nlm.nih.gov/pubmed/31695065 http://dx.doi.org/10.1038/s41598-019-52331-1 |
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