Cargando…
A Molecularly Detailed Na(V)1.5 Model Reveals a New Class I Antiarrhythmic Target
Antiarrhythmic treatment strategies remain suboptimal due to our inability to predict how drug interactions with ion channels will affect the ability of the tissues to initiate and sustain an arrhythmia. We built a multiscale molecular model of the Na(+) channel domain III (domain III voltage-sensin...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834944/ https://www.ncbi.nlm.nih.gov/pubmed/31709321 http://dx.doi.org/10.1016/j.jacbts.2019.06.002 |