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JAK2(V617F)-Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure
Janus kinase 2 (valine to phenylalanine at residue 617) (JAK2(V617F)) mutations lead to myeloproliferative neoplasms associated with elevated myeloid, erythroid, and megakaryocytic cells. Alternatively these same mutations can lead to the condition of clonal hematopoiesis with no impact on blood cel...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834960/ https://www.ncbi.nlm.nih.gov/pubmed/31709318 http://dx.doi.org/10.1016/j.jacbts.2019.05.013 |