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3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

Caloric restriction mimetics (CRMs) are natural or synthetic compounds that mimic the health‐promoting and longevity‐extending effects of caloric restriction. CRMs provoke the deacetylation of cellular proteins coupled to an increase in autophagic flux in the absence of toxicity. Here, we report the...

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Detalles Bibliográficos
Autores principales: Chen, Guo, Xie, Wei, Nah, Jihoon, Sauvat, Allan, Liu, Peng, Pietrocola, Federico, Sica, Valentina, Carmona‐Gutierrez, Didac, Zimmermann, Andreas, Pendl, Tobias, Tadic, Jelena, Bergmann, Martina, Hofer, Sebastian J, Domuz, Lana, Lachkar, Sylvie, Markaki, Maria, Tavernarakis, Nektarios, Sadoshima, Junichi, Madeo, Frank, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835206/
https://www.ncbi.nlm.nih.gov/pubmed/31609086
http://dx.doi.org/10.15252/emmm.201910469