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Reduced Fitness Costs of mcr-1.2 Compared to Mutated pmrB in Isogenic Colistin-Resistant KPC-3-Producing Klebsiella pneumoniae

In the present study, we provide the results of a detailed genomic analysis and the growth characteristics of a colistin-resistant KPC-3-producing Klebsiella pneumoniae sequence type 512 (ST512) isolate (the colR-KPC3-KP isolate) with a mutated pmrB and isogenic isolates of colR-KPC3-KP with mcr-1.2...

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Detalles Bibliográficos
Autores principales: Giordano, Cesira, Klak, Adrian, Barnini, Simona, Chlebowicz, Monika A., Menconi, Mariacristina, Rossen, John W., Friedrich, Alexander W., Bathoorn, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835208/
https://www.ncbi.nlm.nih.gov/pubmed/31694895
http://dx.doi.org/10.1128/mSphere.00551-19