Cargando…
Reduced Fitness Costs of mcr-1.2 Compared to Mutated pmrB in Isogenic Colistin-Resistant KPC-3-Producing Klebsiella pneumoniae
In the present study, we provide the results of a detailed genomic analysis and the growth characteristics of a colistin-resistant KPC-3-producing Klebsiella pneumoniae sequence type 512 (ST512) isolate (the colR-KPC3-KP isolate) with a mutated pmrB and isogenic isolates of colR-KPC3-KP with mcr-1.2...
Autores principales: | Giordano, Cesira, Klak, Adrian, Barnini, Simona, Chlebowicz, Monika A., Menconi, Mariacristina, Rossen, John W., Friedrich, Alexander W., Bathoorn, Erik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835208/ https://www.ncbi.nlm.nih.gov/pubmed/31694895 http://dx.doi.org/10.1128/mSphere.00551-19 |
Ejemplares similares
-
Localized pmrB hypermutation drives the evolution of colistin heteroresistance
por: Kapel, Natalia, et al.
Publicado: (2022) -
An allelic variant of the PmrB sensor kinase responsible for colistin resistance in an Escherichia coli strain of clinical origin
por: Cannatelli, Antonio, et al.
Publicado: (2017) -
Ser253Leu substitution in PmrB contributes to colistin resistance in clinical Acinetobacter nosocomialis
por: Yang, Ya-Sung, et al.
Publicado: (2021) -
The Characterization of Two-Component System PmrA/PmrB in Cronobacter sakazakii
por: Hua, Jingjing, et al.
Publicado: (2020) -
Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa
por: Romano, Keith P., et al.
Publicado: (2019)