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Utilizing a Kidney-Targeting Peptide to Improve Renal Deposition of a Pro-Angiogenic Protein Biopolymer

Elastin-like polypeptides (ELP) are versatile protein biopolymers used in drug delivery due to their modular nature, allowing fusion of therapeutics and targeting agents. We previously developed an ELP fusion with vascular endothelial growth factor (VEGF) and demonstrated its therapeutic efficacy in...

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Detalles Bibliográficos
Autores principales: Mahdi, Fakhri, Chade, Alejandro R., Bidwell, Gene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835230/
https://www.ncbi.nlm.nih.gov/pubmed/31635263
http://dx.doi.org/10.3390/pharmaceutics11100542