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Manufacturing Different Types of Solid Dispersions of BCS Class IV Polyphenol (Daidzein) by Spray Drying: Formulation and Bioavailability

Daidzein (DZ) is a polyphenolic compound belonging to Biopharmaceutical Classification System class IV, which shows that it may have limited therapeutic effects due to its low solubility and poor bioavailability. This study aimed to obtain high-purity DZ and prepare and characterize different types...

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Detalles Bibliográficos
Autores principales: Panizzon, Gean Pier, Giacomini Bueno, Fernanda, Ueda-Nakamura, Tânia, Nakamura, Celso Vataru, Dias Filho, Benedito Prado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835336/
https://www.ncbi.nlm.nih.gov/pubmed/31557831
http://dx.doi.org/10.3390/pharmaceutics11100492