Development of an Aryloxazole Derivative as a Brain-Permeable Anti-Glioblastoma Agent

Glioblastoma drug development has been difficult due to the extremely low blood brain barrier (BBB) penetration of conventional anti-cancer agents. P-glycoprotein, an efflux membrane transporter, is responsible for the poor brain uptake of small and hydrophobic drug substances. To develop brain-pene...

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Detalles Bibliográficos
Autores principales: Shin, Seulgi, Lim, Sungsu, Song, Ji Yeon, Kim, Dohee, Choi, Min Jeong, Gadhe, Changdev G., Park, A Young, Pae, Ae Nim, Kim, Yun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835410/
https://www.ncbi.nlm.nih.gov/pubmed/31569420
http://dx.doi.org/10.3390/pharmaceutics11100497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835410/
https://www.ncbi.nlm.nih.gov/pubmed/31569420
http://dx.doi.org/10.3390/pharmaceutics11100497

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