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Pharmacokinetic Study of Bioactive Glycopeptide from Strongylocentrotus droebachiensis After Intranasal Administration to Rats Using Biomarker Approach

A glycopeptide fraction (GPF) from internal organs of green sea urchins (Strongylocentrotus droebachiensis Müller, Strongylocentrotidae) has been reported to be an effective bronchitis treatment. In this study, we evaluated the pharmacokinetic and tissue distribution of GPF, following single and rep...

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Detalles Bibliográficos
Autores principales: Shikov, Alexander N., Pozharitskaya, Olga N., Faustova, Natalia M., Kosman, Vera M., Makarov, Valery G., Razzazi-Fazeli, Ebrahim, Novak, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835498/
https://www.ncbi.nlm.nih.gov/pubmed/31614490
http://dx.doi.org/10.3390/md17100577