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Quasi-Dynamic Dissolution of Electrospun Polymeric Nanofibers Loaded with Piroxicam

We investigated and monitored in situ the wetting and dissolution properties of polymeric nanofibers and determined the solid-state of a drug during dissolution. Piroxicam (PRX) was used as a low-dose and poorly-soluble model drug, and hydroxypropyl methylcellulose (HPMC) and polydextrose (PD) were...

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Detalles Bibliográficos
Autores principales: Paaver, Urve, Heinämäki, Jyrki, Kassamakov, Ivan, Ylitalo, Tuomo, Hæggström, Edward, Laidmäe, Ivo, Kogermann, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835728/
https://www.ncbi.nlm.nih.gov/pubmed/31554258
http://dx.doi.org/10.3390/pharmaceutics11100491