Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America

The Diabetes Prevention Program (DPP) is effective for the prevention of type 2 diabetes by weight loss with diet and physical activity. However, there is little evidence as to whether this program could be translated into real-world clinical practice in Latin American countries. The objective of th...

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Autores principales: Armenta-Guirado, Brianda, Martínez-Contreras, Teresita, Candia-Plata, Maria C., Esparza-Romero, Julián, Martínez-Mir, Raúl, Haby, Michelle M., Valencia, Mauro E., Díaz-Zavala, Rolando G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835923/
https://www.ncbi.nlm.nih.gov/pubmed/31581478
http://dx.doi.org/10.3390/nu11102324
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author Armenta-Guirado, Brianda
Martínez-Contreras, Teresita
Candia-Plata, Maria C.
Esparza-Romero, Julián
Martínez-Mir, Raúl
Haby, Michelle M.
Valencia, Mauro E.
Díaz-Zavala, Rolando G.
author_facet Armenta-Guirado, Brianda
Martínez-Contreras, Teresita
Candia-Plata, Maria C.
Esparza-Romero, Julián
Martínez-Mir, Raúl
Haby, Michelle M.
Valencia, Mauro E.
Díaz-Zavala, Rolando G.
author_sort Armenta-Guirado, Brianda
collection PubMed
description The Diabetes Prevention Program (DPP) is effective for the prevention of type 2 diabetes by weight loss with diet and physical activity. However, there is little evidence as to whether this program could be translated into real-world clinical practice in Latin American countries. The objective of this work was to evaluate the effectiveness of the DPP for the management of overweightness and obesity at 6 and 12 months in clinical practice in Mexico. This was a non-controlled intervention study implemented in five public clinics in northern Mexico. Two hundred and thirty-seven adults aged 45.7 ± 9.9 years with a Body Mass Index (BMI) of 34.4 ± 5.4 kg/m(2) received group sessions with an adaptation of the DPP, in addition to nutrition counseling. One hundred and thirty-three (56%) participants concluded the 6 month phase. They showed a significant weight loss, ranging from 2.76 ± 4.76 to 7.92 ± 6.85 kg (p ≤ 0.01) in the clinics. The intention-to-treat analysis showed a more conservative weight loss. Participant retention at the end of 12 months was low (40%). The implementation of the DPP in different public clinics in Mexico was effective in the management of obesity in the short term, but better strategies are required to improve participant retention in the long term.
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spelling pubmed-68359232019-11-25 Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America Armenta-Guirado, Brianda Martínez-Contreras, Teresita Candia-Plata, Maria C. Esparza-Romero, Julián Martínez-Mir, Raúl Haby, Michelle M. Valencia, Mauro E. Díaz-Zavala, Rolando G. Nutrients Article The Diabetes Prevention Program (DPP) is effective for the prevention of type 2 diabetes by weight loss with diet and physical activity. However, there is little evidence as to whether this program could be translated into real-world clinical practice in Latin American countries. The objective of this work was to evaluate the effectiveness of the DPP for the management of overweightness and obesity at 6 and 12 months in clinical practice in Mexico. This was a non-controlled intervention study implemented in five public clinics in northern Mexico. Two hundred and thirty-seven adults aged 45.7 ± 9.9 years with a Body Mass Index (BMI) of 34.4 ± 5.4 kg/m(2) received group sessions with an adaptation of the DPP, in addition to nutrition counseling. One hundred and thirty-three (56%) participants concluded the 6 month phase. They showed a significant weight loss, ranging from 2.76 ± 4.76 to 7.92 ± 6.85 kg (p ≤ 0.01) in the clinics. The intention-to-treat analysis showed a more conservative weight loss. Participant retention at the end of 12 months was low (40%). The implementation of the DPP in different public clinics in Mexico was effective in the management of obesity in the short term, but better strategies are required to improve participant retention in the long term. MDPI 2019-10-01 /pmc/articles/PMC6835923/ /pubmed/31581478 http://dx.doi.org/10.3390/nu11102324 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Armenta-Guirado, Brianda
Martínez-Contreras, Teresita
Candia-Plata, Maria C.
Esparza-Romero, Julián
Martínez-Mir, Raúl
Haby, Michelle M.
Valencia, Mauro E.
Díaz-Zavala, Rolando G.
Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America
title Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America
title_full Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America
title_fullStr Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America
title_full_unstemmed Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America
title_short Effectiveness of the Diabetes Prevention Program for Obesity Treatment in Real World Clinical Practice in a Middle-Income Country in Latin America
title_sort effectiveness of the diabetes prevention program for obesity treatment in real world clinical practice in a middle-income country in latin america
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835923/
https://www.ncbi.nlm.nih.gov/pubmed/31581478
http://dx.doi.org/10.3390/nu11102324
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