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The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity

Drug hypersensitivity reactions that resemble acute immune reactions are linked to certain human leucocyte antigen (HLA) alleles. Severe and life-threatening Stevens Johnson Syndrome and Toxic Epidermal Necrolysis following treatment with the antiepileptic and psychotropic drug Carbamazepine are ass...

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Detalles Bibliográficos
Autores principales: Simper, Gwendolin S., Gräser, Lareen S., Celik, Alexander A., Kuhn, Joachim, Kunze-Schumacher, Heike, Hò, Gia-Gia T., Blasczyk, Rainer, Pich, Andreas, Bade-Doeding, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835980/
https://www.ncbi.nlm.nih.gov/pubmed/31618895
http://dx.doi.org/10.3390/pharmaceutics11100536