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The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity
Drug hypersensitivity reactions that resemble acute immune reactions are linked to certain human leucocyte antigen (HLA) alleles. Severe and life-threatening Stevens Johnson Syndrome and Toxic Epidermal Necrolysis following treatment with the antiepileptic and psychotropic drug Carbamazepine are ass...
Autores principales: | Simper, Gwendolin S., Gräser, Lareen S., Celik, Alexander A., Kuhn, Joachim, Kunze-Schumacher, Heike, Hò, Gia-Gia T., Blasczyk, Rainer, Pich, Andreas, Bade-Doeding, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835980/ https://www.ncbi.nlm.nih.gov/pubmed/31618895 http://dx.doi.org/10.3390/pharmaceutics11100536 |
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