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Antiamoebic Activities of Indolocarbazole Metabolites Isolated from Streptomyces sanyensis Cultures

Indolocarbazoles are a family of natural alkaloids characterized by their potent protein kinase and topoisomerase I inhibitory activity. Among them, staurosporine (1) has exhibited promising inhibitory activity against parasites. Based on new insights on the activity and mechanism of action of STS i...

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Detalles Bibliográficos
Autores principales: Cartuche, Luis, Reyes-Batlle, María, Sifaoui, Ines, Arberas-Jiménez, Iñigo, Piñero, José E., Fernández, José J., Lorenzo-Morales, Jacob, Díaz-Marrero, Ana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836125/
https://www.ncbi.nlm.nih.gov/pubmed/31627366
http://dx.doi.org/10.3390/md17100588