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Platelets promote breast cancer cell MCF-7 metastasis by direct interaction: surface integrin α2β1-contacting-mediated activation of Wnt-β-catenin pathway

BACKGROUND: Integrin-mediated platelet-tumor cell contacting plays an important role in promoting epithelial-mesenchymal transition (EMT) transformation of tumor cells and cancer metastasis, but whether it occurs in breast cancer cells is not completely clear. OBJECTIVE: The purpose of this study wa...

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Detalles Bibliográficos
Autores principales: Zuo, Xiao-xiao, Yang, Ya, Zhang, Yue, Zhang, Zhi-gang, Wang, Xiao-fei, Shi, Yong-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836423/
https://www.ncbi.nlm.nih.gov/pubmed/31699102
http://dx.doi.org/10.1186/s12964-019-0464-x