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Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits

AIM: In acute respiratory distress syndrome (ARDS) damaged alveolar epithelium, leakage of plasma proteins into the alveolar space and inactivation of pulmonary surfactant lead to respiratory dysfunction. Lung function could potentially be restored with exogenous surfactant therapy, but clinical tri...

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Detalles Bibliográficos
Autores principales: Zebialowicz Ahlström, J., Massaro, F., Mikolka, P., Feinstein, R., Perchiazzi, G., Basabe-Burgos, O., Curstedt, T., Larsson, A., Johansson, J., Rising, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836435/
https://www.ncbi.nlm.nih.gov/pubmed/31694668
http://dx.doi.org/10.1186/s12931-019-1220-x