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Synthetic surfactant with a recombinant surfactant protein C analogue improves lung function and attenuates inflammation in a model of acute respiratory distress syndrome in adult rabbits
AIM: In acute respiratory distress syndrome (ARDS) damaged alveolar epithelium, leakage of plasma proteins into the alveolar space and inactivation of pulmonary surfactant lead to respiratory dysfunction. Lung function could potentially be restored with exogenous surfactant therapy, but clinical tri...
Autores principales: | Zebialowicz Ahlström, J., Massaro, F., Mikolka, P., Feinstein, R., Perchiazzi, G., Basabe-Burgos, O., Curstedt, T., Larsson, A., Johansson, J., Rising, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836435/ https://www.ncbi.nlm.nih.gov/pubmed/31694668 http://dx.doi.org/10.1186/s12931-019-1220-x |
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