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Role of protein arginine methyltransferase 5 in group 3 (MYC-driven) Medulloblastoma

BACKGROUND: MYC amplification or overexpression is common in Group 3 medulloblastoma and is associated with the worst prognosis. Recently, protein arginine methyl transferase (PRMT) 5 expression has been closely associated with aberrant MYC function in various cancers, including brain tumors such as...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Nagendra K., Mahapatra, Sidharth, Kesherwani, Varun, Kling, Matthew J., Shukla, Mamta, Ray, Sutapa, Kanchan, Ranjana, Perumal, Naveenkumar, McGuire, Timothy R., Sharp, J. Graham, Joshi, Shantaram S., Coulter, Don W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836472/
https://www.ncbi.nlm.nih.gov/pubmed/31694585
http://dx.doi.org/10.1186/s12885-019-6291-z