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Role of protein arginine methyltransferase 5 in group 3 (MYC-driven) Medulloblastoma
BACKGROUND: MYC amplification or overexpression is common in Group 3 medulloblastoma and is associated with the worst prognosis. Recently, protein arginine methyl transferase (PRMT) 5 expression has been closely associated with aberrant MYC function in various cancers, including brain tumors such as...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836472/ https://www.ncbi.nlm.nih.gov/pubmed/31694585 http://dx.doi.org/10.1186/s12885-019-6291-z |