Cargando…

Role of protein arginine methyltransferase 5 in group 3 (MYC-driven) Medulloblastoma

BACKGROUND: MYC amplification or overexpression is common in Group 3 medulloblastoma and is associated with the worst prognosis. Recently, protein arginine methyl transferase (PRMT) 5 expression has been closely associated with aberrant MYC function in various cancers, including brain tumors such as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chaturvedi, Nagendra K., Mahapatra, Sidharth, Kesherwani, Varun, Kling, Matthew J., Shukla, Mamta, Ray, Sutapa, Kanchan, Ranjana, Perumal, Naveenkumar, McGuire, Timothy R., Sharp, J. Graham, Joshi, Shantaram S., Coulter, Don W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836472/ https://www.ncbi.nlm.nih.gov/pubmed/31694585 http://dx.doi.org/10.1186/s12885-019-6291-z

Ejemplares similares

Improved therapy for medulloblastoma: targeting hedgehog and PI3K-mTOR signaling pathways in combination with chemotherapy
por: Chaturvedi, Nagendra K., et al.
Publicado: (2018)

Long non-coding RNA profiling of pediatric Medulloblastoma
por: Kesherwani, Varun, et al.
Publicado: (2020)

A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma
por: Kling, Matthew J., et al.
Publicado: (2022)

MEDB-87. Transcriptome-driven drug repurposing in group 3 medulloblastoma
por: Doss, David, et al.
Publicado: (2022)

MDB-40. TRANSCRIPTOME-BASED DRUG REPURPOSING IN GROUP 3 MEDULLOBLASTOMA
por: Doss, David, et al.
Publicado: (2023)

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery
por: Kling, Matthew J., et al.
Publicado: (2020)

MEDB-89. Elucidation of the Oncogenic role of Nuclear Factor I/B (NFIB) in group 3 medulloblastoma
por: Perumal, Naveenkumar, et al.
Publicado: (2022)

MBRS-72. MiR-212 FUNCTIONS AS A TUMOR SUPPRESSOR GENE IN GROUP 3 MEDULLOBLASTOMA VIA TARGETING NUCLEAR FACTOR I/B (NFIB)
por: Perumal, Naveenkumar, et al.
Publicado: (2020)

MBRS-13. MiR-1253 POTENTIATES CISPLATIN RESPONSE IN PEDIATRIC MEDULLOBLASTOMA BY REGULATING FERROPTOSIS
por: Kanchan, Ranjana K, et al.
Publicado: (2020)

Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment
por: Ray, Sutapa, et al.
Publicado: (2021)

BIOL-07. MIR-212 FUNCTIONS AS A TUMOR SUPPRESSOR GENE IN GROUP 3 MEDULLOBLASTOMA VIA TARGETING NUCLEAR FACTOR I/B (NFIB)
por: Perumal, Naveenkumar, et al.
Publicado: (2021)

MDB-34. “INDUCING IRON IMBALANCE BY TARGETING THE ABCB7/GPX4 AXIS ACCELERATES FERROPTOSIS IN MEDULLOBLASTOMA”
por: Kanchan, Ranjana, et al.
Publicado: (2023)

BIOL-06. MIR-1253 POTENTIATES CISPLATIN RESPONSE IN PEDIATRIC GROUP 3 MEDULLOBLASTOMA BY REGULATING FERROPTOSIS
por: Kanchan, Ranjana, et al.
Publicado: (2021)

MEDB-90. Iron Imbalance Can Potentiate Cisplatin Response in Pediatric Medulloblastoma by Regulating Ferroptosis
por: Kanchan, Ranjana, et al.
Publicado: (2022)

Improved therapy for neuroblastoma using a combination approach: superior efficacy with vismodegib and topotecan
por: Chaturvedi, Nagendra K., et al.
Publicado: (2016)

MiR‐1253 exerts tumor‐suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7‐H3)
por: Kanchan, Ranjana K., et al.
Publicado: (2020)

STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo
por: Rohrer, Kyle A., et al.
Publicado: (2023)

MiR-212-3p functions as a tumor suppressor gene in group 3 medulloblastoma via targeting nuclear factor I/B (NFIB)
por: Perumal, Naveenkumar, et al.
Publicado: (2021)

Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression
por: Wynn, Daniel T, et al.
Publicado: (2022)

Synergistic efficacy of inhibiting MYCN and mTOR signaling against neuroblastoma
por: Kling, Matthew J., et al.
Publicado: (2021)

MDB-45. SELECTIVE B7-H3 INHIBITORS NI1 AND NI4 REDUCE AGGRESSIVENESS OF GROUP 3 MEDULLOBLASTOMA
por: Krishnan, Prakadeeswari Gopala, et al.
Publicado: (2023)

The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells
por: Favia, Annarita, et al.
Publicado: (2019)

Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis
por: Kumar, Vinod, et al.
Publicado: (2018)

Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells
por: Mongiardi, Maria Patrizia, et al.
Publicado: (2015)

Protein arginine methyltransferase 6 is a novel substrate of protein arginine methyltransferase 1
por: Cao, Meng-Tong, et al.
Publicado: (2023)

The Role and Mechanism of Lysine Methyltransferase and Arginine Methyltransferase in Kidney Diseases
por: Zhou, Xun, et al.
Publicado: (2022)

MBRS-64. STUDY OF ARGININE METHYL TRANSFERASES IN MEDULLOBLASTOMA
por: Cheng, Donghang, et al.
Publicado: (2020)

Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513
por: Coulter, Don W., et al.
Publicado: (2016)

N-myc gene expression and oncoprotein characterisation in medulloblastoma.
por: Garson, J. A., et al.
Publicado: (1989)

Mouse medulloblastoma driven by CRISPR activation of cellular Myc
por: Vo, BaoHan T., et al.
Publicado: (2018)

OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA
por: Schmidt, Christin, et al.
Publicado: (2021)

Targeting protein folding in N‐Myc‐driven medulloblastoma
por: Valinciute, Gintvile, et al.
Publicado: (2023)

Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor
por: Feoli, Alessandra, et al.
Publicado: (2023)

Structural biology and chemistry of protein arginine methyltransferases
por: Schapira, Matthieu, et al.
Publicado: (2014)

The Role of Protein Arginine Methyltransferases in Inflammatory Responses
por: Kim, Ji Hye, et al.
Publicado: (2016)

Protein Arginine Methyltransferases in Neuromuscular Function and Diseases
por: Lee, Jinwoo, et al.
Publicado: (2022)

c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients
por: von Bueren, André O, et al.
Publicado: (2011)

microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy
por: Kanchan, Ranjana K., et al.
Publicado: (2020)

Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition
por: Graziani, Vittoria, et al.
Publicado: (2023)

Burkitt lymphoma beyond MYC translocation: N-MYC and DNA methyltransferases dysregulation
por: De Falco, Giulia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_3bbf1380o09mk6s84c8rrqcfk9