Loss-of-function phenotype of a PKCθ(T219A) knockin mouse strain

BACKGROUND: Protein kinase C θ has been established as an important signaling intermediate in T-effector-cell activation and survival pathways by controlling activity of the key transcription factors NF-κB and NFAT. Previous studies identified an activation-induced auto-phosphorylation site at Thr-2...

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Detalles Bibliográficos
Autores principales: Thuille, Nikolaus, Siegmund, Kerstin, Klepsch, Victoria, Schörgenhuber, Jacqueline, Danklmaier, Sarah, Leitges, Michael, Baier, Gottfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836476/
https://www.ncbi.nlm.nih.gov/pubmed/31694643
http://dx.doi.org/10.1186/s12964-019-0466-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836476/
https://www.ncbi.nlm.nih.gov/pubmed/31694643
http://dx.doi.org/10.1186/s12964-019-0466-8

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