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Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression

The glucocorticoid receptor (NR3C1, also known as GR) binds to specific DNA sequences and directly induces transcription of anti-inflammatory genes that contribute to cytokine repression, frequently in cooperation with NF-kB. Whether inflammatory repression also occurs through local interactions bet...

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Detalles Bibliográficos
Autores principales: Sasse, Sarah K., Gruca, Margaret, Allen, Mary A., Kadiyala, Vineela, Song, Tengyao, Gally, Fabienne, Gupta, Arnav, Pufall, Miles A., Dowell, Robin D., Gerber, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836729/
https://www.ncbi.nlm.nih.gov/pubmed/31519741
http://dx.doi.org/10.1101/gr.248187.119