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Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression
The glucocorticoid receptor (NR3C1, also known as GR) binds to specific DNA sequences and directly induces transcription of anti-inflammatory genes that contribute to cytokine repression, frequently in cooperation with NF-kB. Whether inflammatory repression also occurs through local interactions bet...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836729/ https://www.ncbi.nlm.nih.gov/pubmed/31519741 http://dx.doi.org/10.1101/gr.248187.119 |