PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data

Available computational methods for tumor phylogeny inference via single-cell sequencing (SCS) data typically aim to identify the most likely perfect phylogeny tree satisfying the infinite sites assumption (ISA). However, the limitations of SCS technologies including frequent allele dropout and vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Malikic, Salem, Mehrabadi, Farid Rashidi, Ciccolella, Simone, Rahman, Md. Khaledur, Ricketts, Camir, Haghshenas, Ehsan, Seidman, Daniel, Hach, Faraz, Hajirasouliha, Iman, Sahinalp, S. Cenk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836735/
https://www.ncbi.nlm.nih.gov/pubmed/31628256
http://dx.doi.org/10.1101/gr.234435.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836735/
https://www.ncbi.nlm.nih.gov/pubmed/31628256
http://dx.doi.org/10.1101/gr.234435.118

Ejemplares similares