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Identification and dynamic quantification of regulatory elements using total RNA

The spatial and temporal regulation of transcription initiation is pivotal for controlling gene expression. Here, we introduce capped-small RNA-seq (csRNA-seq), which uses total RNA as starting material to detect transcription start sites (TSSs) of both stable and unstable RNAs at single-nucleotide...

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Detalles Bibliográficos
Autores principales: Duttke, Sascha H., Chang, Max W., Heinz, Sven, Benner, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836739/
https://www.ncbi.nlm.nih.gov/pubmed/31649059
http://dx.doi.org/10.1101/gr.253492.119