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Genes essential for embryonic stem cells are associated with neurodevelopmental disorders

Mouse embryonic stem cells (mESCs) are key components in generating mouse models for human diseases and performing basic research on pluripotency, yet the number of genes essential for mESCs is still unknown. We performed a genome-wide screen for essential genes in mESCs and compared it to screens i...

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Detalles Bibliográficos
Autores principales: Shohat, Shahar, Shifman, Sagiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836742/
https://www.ncbi.nlm.nih.gov/pubmed/31649057
http://dx.doi.org/10.1101/gr.250019.119