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Genes essential for embryonic stem cells are associated with neurodevelopmental disorders
Mouse embryonic stem cells (mESCs) are key components in generating mouse models for human diseases and performing basic research on pluripotency, yet the number of genes essential for mESCs is still unknown. We performed a genome-wide screen for essential genes in mESCs and compared it to screens i...
Autores principales: | Shohat, Shahar, Shifman, Sagiv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836742/ https://www.ncbi.nlm.nih.gov/pubmed/31649057 http://dx.doi.org/10.1101/gr.250019.119 |
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